A former San Francisco police detective suffering from an extreme case of obsessive-compulsive disorder is called in to investigate an apparent assassination attempt of a mayoral candidate in which one of his bodyguards is killed.
With an introduction to Monk's talent, his phobia's, and need for an assistant, Monk investigates the murder of the candidate bodyguard and a political worker. He determines the candidate was not the intended target.
When a woman drives off the road to her death, her body is mysteriously found the next morning by a psychic known for fudging the truth. Monk must discover if she's telling the truth this time, or else let a murderer go free.
A judge is murdered while placing a 911 call, but before she dies she names her attacker - notorious criminal Dale Biederbeck. The problem is, "Dale the Whale" is over 800 pounds and hasn't left his bed in years.
A burglar becomes infected with a deadly virus. Dr. Sloan and Jesse are subsequently exposed to the virus and are confined to Mark's home while Steve and Amanda investigate a drug company to discover an antidote.
A taunting clue left for Aurora at a meeting begins a cat-and-mouse game between her and a mysterious criminal who commits increasingly serious crimes that leave the town rattled. Candace Cameron Bure, Niall Matter, Marilu Henner.
When Sally's wealthy aunt Gladys, dies from poisoning after giving a wedding toast, Aurora inspects if Glady's will hints at who may have wanted her gone. Stars Candace Cameron Bure, Niall Matter, Marilu Henner.