Monk attends a popular new play starring Sharona's sister Gail. But when Gail appears to stab and kill her costar during the live performance, Sharona calls Monk in to investigate.
A series of mail bombs target three wealthy siblings, but Monk thinks one of the brothers is actually responsible. The problem is, he's been in a coma for the last four months.
One police officer is accidentally shot by another during a raid gone wrong. Dr. Sloan investigates the victim's wife, the shooter, and a conniving lawyer when he suspects foul play.
A burglar becomes infected with a deadly virus. Dr. Sloan and Jesse are subsequently exposed to the virus and are confined to Mark's home while Steve and Amanda investigate a drug company to discover an antidote.
Monk's agoraphobic brother Ambrose asks for his help, convinced his neighbor has been killed by her husband. But all the husband seems focused on is winning the pies at the local fair.
Jane helps a beauty pageant contestant who insists the results are rigged. Kim represents her estranged dad when he loses his youth baseball coaching job.
As Jane tries to keep a friend's fiancé from being deported on the eve of their wedding, Kim goes into labor while representing a writer whose erotic novel was plagiarized by a big publisher.
Caterer Goldy Berry reunites with detective Tom Schultz when a realtor is murdered. As they uncover personal and professional rivalries, they realize the culprit is closer than expected. Stars Nikki DeLoach, Andrew Walker.
Jenn buys an old reel-to-reel recorder at a garage sale only to find that it includes the sound of a man pleading for his life. Jenn's investigation leads to other patients.