After Stottlemeyer, Disher and Monk are shredded on the stand in a murder case, causing the accused to go free, Monk loses his confidence. Meanwhile, Disher tries to help a boy he used to mentor who is accused of another murder.
Jane fights to stop a drug company from discontinuing the drug trial that is keeping an eight-year-old cancer patient alive. Kim represents a high school friend whose vengeful ex has posted nude photos of her on the Internet.
Jennifer Shannon has an eye for antiques and a mind for solving mysteries. When she buys a storage unit at auction, she has no idea she's opening the door to murder, and realizes the killer is after something in the storage unit.